2018-04-19 12:12:332025-05-25 19:10:17
description
mother-cell specific penicillin-binding protein (spore cortex)
mother-cell specific class B penicillin-binding protein (spore cortex)
locus
BSU15170
BSU_15170
proteinLength
645
646
geneLength
1935
1941
function
spore morphogenesis
synthesis of spore peptidoglycan
outlinks
bsu
BSU15170
BSU_15170
Gene
Coordinates
1,584,214 → 1,586,154
1,584,214 1,586,154
The protein
Catalyzed reaction/ biological activity
protects [[protein|SpoVE]] from proteolytic degradation [Pubmed|20417640]
synthesis of spore peptidoglycan [pubmed|8289242]
protects [[protein|SpoVE]] from proteolytic degradation [Pubmed|20417640]
The protein
[SW|Localization]
intermembrane space that separates forespores from mother cells [Pubmed|19919673]
intermembrane space that separates forespores from mother cells [Pubmed|19919673]
outer forespore membrane [pubmed|20417640]
Biological materials
Mutant
1A975 ( ''spoVD''::''cat''), [Pubmed|19212404], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A975&Search=1A975 BGSC]
BKE15170 (Δ[[gene|spoVD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE15170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGAGACCGTTCACTCCTT, downstream forward: _UP4_TGATTCGGGCTGCCTATTCT
BKK15170 (Δ[[gene|spoVD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK15170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGAGACCGTTCACTCCTT, downstream forward: _UP4_TGATTCGGGCTGCCTATTCT
1A975 ( ''spoVD''::''cat''), [Pubmed|19212404], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A975&Search=1A975 BGSC]
BKE15170 ([[gene|spoVD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE15170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGAGACCGTTCACTCCTT, downstream forward: _UP4_TGATTCGGGCTGCCTATTCT
BKK15170 ([[gene|spoVD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK15170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGAGACCGTTCACTCCTT, downstream forward: _UP4_TGATTCGGGCTGCCTATTCT
References
Original Publications
The protein
Protein family
[SW|transpeptidase family] (according to UniProt)
The protein
Structure
[PDB|1PYY] (PBP2B from Spreptococcus pneumoniae, 26% identity) [pubmed|12923202]